The Technology: Dr. Andrew Bean at the University of Texas Health Science Center at Houston, has developed a monoclonal antibody to STAM. STAM is a protein that plays a role in the movement of proteins into lysosome for degradation. Cellular expression of STAM can be determined using this monoclonal antibody, therefore this antibody will be useful in determining how STAM is regulated and in characterizing STAM interactions during endocytosis.
Publications:
Sun, W., Vida, T.A., Sirisaengtaksin, N., Merrill, S.A., Hanson, P.L, and Bean, AJ., Cell-free reconstitution of multi-vesicular body formation and receptor sorting, Traffic, 2010 Jun; 11 (6):867-76. PMID: 20214752
The preceding is intended to be a non-confidential summary of a novel technology created at the University of Texas Health Science Center at Houston (UTHealth).
UTHealth Ref. No.: 2010-0024
Inventors: Dr. Andrew Bean
License Available: world-wide, non-exclusive
To obtain further information about this technology, please contact:
Office of Technology Management, 7000 Fannin, Suite 720, Houston, TX, 77030
Phone: (713) 500-3369 Fax: (713) 500-0331
Email: uthsch-otm@uth.tmc.edu