Search Results - Research Materials

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Di-functional Hyaluronic Acid for Tissue Engineering
Hyaluronic Acid (HA) is a polysaccharide that is expressed in the extracellular matrix (ECM) of all vertebrate tissues, contributing to the development of cells in tissue. HA based hydrogels are useful tools in tissue engineering as the HA can be modified with bioactive peptides to facilitate the growth, differentiation and attachment of stem cell...
Published: 4/14/2017   |   Inventor(s): Laura Smith callahan, Hyun ju Lim
Keywords(s):  
Category(s): Drug Delivery, Research Materials, Therapeutics
Novel Channelrhodopsins for Inhibition of Neuronal Activity
Optogenetics is rapidly evolving field that provides the ability to control neurons using light-sensitive proteins called channelrhodopsins (ChRs). When genetically expressed in neurons, ChRs have the ability to selectively manipulate neuronal activity in a light-dependent manner. Gene-therapy using ChRs has the exciting potential to be used to tre...
Published: 7/13/2016   |   Inventor(s): John Spudich, Elena g Govorunova, Oleg a Sineshchekov
Keywords(s):  
Category(s): Therapeutics, Research Materials
Enterotoxigenic Escherichia coli Isolates Identified from Patients with Travelers' Diarrhea
Market: Traveler’s diarrhea is the most common illness affecting travelers, and affects as many as 800 million people a year.  The most common causative agent of traveler’s diarrhea is Enterotoxigenic E. coli. Toxins secreted by these bacteria result in severe watery diarrhea. The Technology: Researchers at the University of Texas Healt...
Published: 6/24/2014   |   Inventor(s):  
Keywords(s):  
Category(s): Research Materials
Red and Blue Shifted Channelrhodopsins
Channelrhodopsins (ChRs) are a type of optogenetic tool that have enabled targeted light-activation of neuron firing in tissue culture and in living organisms. Dr. John Spudich at the University of Texas Health Science Center at Houston has characterized several ChRs whose properties make them particularly useful for photocontrol of neuron firing, ...
Published: 6/15/2012   |   Inventor(s):  
Keywords(s):  
Category(s): Research Materials
Anti-STAM Monoclonal Antibodies
The Technology: Dr. Andrew Bean at the University of Texas Health Science Center at Houston, has developed a monoclonal antibody to STAM. STAM is a protein that plays a role in the movement of proteins into lysosome for degradation. Cellular expression of STAM can be determined using this monoclonal antibody, therefore this antibody will ...
Published: 1/5/2012   |   Inventor(s):  
Keywords(s):  
Category(s): Research Materials
Targeting Tumors by Pattern Recognition: A Paradigm shift in Targeted Therapeutics
Market: The American Cancer Society estimates that more than 500,000 people will die from cancer in the U.S. in 2007. Many cancer deaths, specifically from cancers of the colon, breast, rectum, and uterine cervix cancers, could be significantly reduced with earlier detection and improved therapy. Cancer treatment of the 15 most common cancers accou...
Published: 11/29/2011   |   Inventor(s):  
Keywords(s):  
Category(s): Research Materials, Therapeutics
SUMO-Specific Protease Nucleotides and Proteins for Diagnosing Hyperpoliferative Diseases
Market: Prostate cancer is the second most common cancer, and second leading cause of cancer death, in American men. The American Cancer Society predicts over 186,000 new diagnoses of prostate cancer, and over 28,000 deaths in the US in 2008. With early detection being key to a better prognosis, a significant number of people are demanding fast...
Published: 11/29/2011   |   Inventor(s):  
Keywords(s): Antibodies, Cancer, Diagnostics, Research tool, Therapeutics
Category(s): Diagnostics, Research Materials, Therapeutics
Structure of Proline- and Arginine-Rich Peptides that Lead to Inhibition of Inflammation and Induction of Angiogenesis
The Technology: PR39, a naturally produced proline-and-arginine-rich peptide consisting of 39 amino acids, induces angiogenesis and reduces inflammation in mouse models. Through structural and biochemical investigations of PR11, a truncated form of PR39, researchers at the University of Texas Health Science Center at Houston (UTHSC-H) have ide...
Published: 11/29/2011   |   Inventor(s):  
Keywords(s):  
Category(s): Research Materials, Therapeutics
HRS/HRS-2 Polyclonal Antibody
Polyclonal Antibodies Against HRS The Technology: Dr. Andrew Bean at the University of Texas Health Science Center at Houston (UTHealth) has developed a polyclonal antibody to Hrs. Hrs is a protein that plays a role in the growth factor signaling pathways. Cellular expression of hrs-2 can be determined via the polyclonal Hrs antibody. This anti...
Published: 11/3/2011   |   Inventor(s):  
Keywords(s):  
Category(s): Research Materials
Immuno-Diagnosis of Lyme Disease
Market: Approximately 20,000 cases of Lyme disease in humans are reported per year in the United States. Lyme disease is the most common tick-borne disease in the US and is also a significant veterinary problem due to a high infection rate of dogs and other domestic animals in endemic regions. The European market is equal to or greater than the ...
Published: 11/3/2011   |   Inventor(s):  
Keywords(s):  
Category(s): Diagnostics, Research Materials
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