The Technology: Dr. Andrew Bean at the University of Texas Health Science Center at Houston (UTHealth) has developed a polyclonal antibody to Hrs. Hrs is a protein that plays a role in the growth factor signaling pathways. Cellular expression of hrs-2 can be determined via the polyclonal Hrs antibody. This antibody will be useful in determining the relationship between growth factor receptor tyrosine kinases and tyrosine phosphorylation of Hrs.
Publications:• Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain. Mol Cell Biol. 1995 Nov;15(11):6213-21.
UTHealth Ref. No.: 2002-0010Inventors: Andrew BeanLicense Available: world-wide; non-exclusive