"WAND-SEEKER" Chronic occlusion re-entry device



In the reverse CART technique, a catheter and a wire are positioned on opposite sides of the coronary occlusion. Through different manipulation of the catheter and the wire, the wire is, ultimately, aligned with the tip of the antegrade catheter, crosses the occluded coronary segment, and gets “externalized” converting a CTO in a regular PCI. Unfortunately, it is not always straightforward to cross the retrograde wire into the antegrade catheter tip to externalize the retrograde wire as a mean to convert the re-CART in a conventional PCI.

New Device Features

The new device and system can facilitate the alignment, crossing and wire re-entry in the antegrade guiding catheter with reduction in time, radiation exposure for the patient/operator, risk of coronary perforation, and the need for “investment procedure”. The new technology uses a guiding catheter who enables the formation of a “wire bias” on one side of the occlusion (e.g., the retrograde side) so that the crossing wire on the retrograde side can be externalized through or around the occlusion toward the guiding catheter. The wire bias will direct  the tip of the wire toward the tip of the antegrade catheter as an additional help  to the tactile and visual feedbacks commonly utilized in retrograde crossing of a coronary occlusion.

Potential Advantages

1. Increase success rate in re-CART

2. Reduced procedural time/ radiation exposure for the patient/operator

3. Reduced risk of perforation of the coronary artery

4. Alternative device/mechanism to existing re-entry devices


Potential Applications

Coronary Procedures, including sub-intimal space application

Vascular Procedures, including peripheral





Angelo Nascimbene, MD


Intellectual Property Status

PCT/US2019/064324 Filed; available for licensing


Stage of Development

Early, preclinical


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Patent Information:

The preceding is intended to be a non-confidential and limited description of a novel technology created at the University of Texas Health Science Center at Houston (UTHealth). This promotional material is not comprehensive in scope and should not replace company’s diligence in a thorough evaluation of the technology. Please contact the Office of Technology Management for more information regarding this technology.
Medical Devices
For Information, Contact:
Christine Flynn
Associate Director, Licensing and New Venture Development
University of Texas Health Science Center At Houston
Angelo Nascimbene
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