Search Results - Diagnostics

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Methods and composition for novel anti-cancer treatments

Background: The Wnt signaling pathway plays essential roles in development and is frequently hyperactivated in cancer cells as a driving mechanism. Nearly 90% of colon cancers, for examples are mutated in this pathway. However, direct targeting of this pathway for cancer drug discovery has been challenging due to receptor redundancy and compl...

Published: Mar 25, 2013 | Inventor(s):

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Category(s): Therapeutics, Diagnostics

Nanoporous and Mesoporous Substrates for Analytical Methods and Methods for Fractionation, Stabilization, and Storage of Biomolecules

Background: A common problem that arises during analysis of biological samples is interference due to highly abundant substances in the samples that can mask the existence of other substances in the mixture. Common examples of this issue are in samples of blood (serum/plasma) and saliva where high concentrations of albumin can create problems ...

Published: Feb 1, 2013 | Inventor(s):

Keywords(s): Devices, Diagnostics, Nanotechnology

Category(s): Diagnostics, Medical Devices, Research Materials

Lymphatic Imaging System

Market: In 2009 there were approximately 1.5 million cases of cancer diagnosed in the United States alone. Some portion of this patient population will develop lymphedemia due to damage to the lymphatic system from their treatment. This condition is characterized by fibrosis from localized fluid retention and tissue swelling. Some clini...

Published: Jan 23, 2012 | Inventor(s):

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Category(s): Diagnostics, Medical Devices

Method of Identifying Patients at Risk of Elevated Intracranial Pressure

Market: The CDC estimates that 1.4 million people are treated for traumatic brain injury (TBI) in the United States each year. Of this patient population, a certain portion will, for reasons not fully understood, develop elevated intracranial pressure (ICP), and this secondary pathology is a major contributor to morbidity and mortality. If pati...

Published: Nov 29, 2011 | Inventor(s):

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Category(s): Diagnostics

SUMO-Specific Protease Nucleotides and Proteins for Diagnosing Hyperpoliferative Diseases

Market: Prostate cancer is the second most common cancer, and second leading cause of cancer death, in American men. The American Cancer Society predicts over 186,000 new diagnoses of prostate cancer, and over 28,000 deaths in the US in 2008. With early detection being key to a better prognosis, a significant number of people are demanding fast...

Published: Nov 29, 2011 | Inventor(s):

Keywords(s): Cancer, Diagnostics, Therapeutics, Antibodies, Research tool

Category(s): Diagnostics, Research Materials, Therapeutics

Splice Variant of Thyroid Stimulating Hormone-Beta (THS-Beta) for Diagnosing and Treating Thyroid Diseases

Splice Variant of thyroid stimulating hormone-beta (TSHb) for diagnosing and treating thyroid diseases Background: Thyroid Disease is a medical condition impairing the function of the thyroid. The thyroid gland takes iodine from the diet and produces thyroid hormone; this hormone affects a person’s physical energy, tempera...

Published: Nov 29, 2011 | Inventor(s):

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Category(s): Diagnostics, Therapeutics

VMP Like Sequences of Pathogenic Borrelia

IMMUNO-DIAGNOSIS OF LYME DISEASE Market: Approximately 20,000 cases of Lyme disease in humans are reported per year in the United States. Lyme disease is the most common tick-borne disease in the US and is also a significant veterinary problem due to a high infection rate of dogs and other domestic animals in endemic regions. The Europea...

Published: Nov 3, 2011 | Inventor(s):

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Category(s): Diagnostics, Research Materials

A Method for Generating Poroelastograms in Vivo

A METHOD FOR GENERATING POROELASTOGRAMS IN VIVO Background: Ultrasound elastograms in are generated by cross-correlating the sequentially-acquired post compression ultrasound data with the reference pre-compression ultrasound data, thus generating an image that allows for differentiation of tissues types, i.e. benign vs. malignant tumors. A...

Published: Oct 24, 2011 | Inventor(s):

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Category(s): Medical Devices, Software, Diagnostics

Enhancing MRI Contrast by Geometric Confinement of Small Imaging Agents within Nanoporous Particles

MRI Contrast Agents in NanoPorous Particles Market: Physicians use magnetic resonance imaging (MRI) to examine the state of a patient’s internal organs. Typically, MRI is performed to evaluate the state of a patient’s brain and spinal cord, heart and blood vessels, bones and joints, and other internal organs. The current market for M...

Published: Oct 19, 2011 | Inventor(s):

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Category(s): Diagnostics

Method to perform Axial-shear strain imaging for tumor classification

AXIAL SHEAR STRAIN ELASTOGRAPHY (ASSE) Background: Ultrasound elastography, now a well-established diagnostic technique, is expanding into everyday ultrasound machines used in all types of clinical practice. The basic elastography technique involves two images of a tissue in question – the first in a normal “before” state and the second af...

Published: Oct 18, 2011 | Inventor(s):

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Category(s): Diagnostics, Medical Devices, Software

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