Search Results - Diagnostics

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HER3 specific monoclonal antibodies for diagnosis and therapeutic use
Background HER-3 is a receptor in the tyrosine kinase family that is a key oncogenic protein in breast cancer as well as other cancers. HER-3 is centrally involved in signaling leading to tumor growth and has been implicated in resistance to cancer treatments, making it an attractive target for cancer therapies. Several drugs, including some in c...
Published: Nov 10, 2014   |   Inventor(s):  
Category(s): Therapeutics, Diagnostics
Methods and composition for novel anti-cancer treatments
Background: The Wnt signaling pathway plays essential roles in development and is frequently hyperactivated in cancer cells as a driving mechanism. Nearly 90% of colon cancers, for examples are mutated in this pathway. However, direct targeting of this pathway for cancer drug discovery has been challenging due to receptor redundancy and compl...
Published: Mar 25, 2013   |   Inventor(s):  
Category(s): Therapeutics, Diagnostics
SUMO-Specific Protease Nucleotides and Proteins for Diagnosing Hyperpoliferative Diseases
Market: Prostate cancer is the second most common cancer, and second leading cause of cancer death, in American men. The American Cancer Society predicts over 186,000 new diagnoses of prostate cancer, and over 28,000 deaths in the US in 2008. With early detection being key to a better prognosis, a significant number of people are demanding fast...
Published: Nov 29, 2011   |   Inventor(s):  
Keywords(s): Cancer, Diagnostics, Therapeutics, Antibodies, Research tool
Category(s): Diagnostics, Research Materials, Therapeutics
Immuno-Diagnosis of Lyme Disease
Market: Approximately 20,000 cases of Lyme disease in humans are reported per year in the United States. Lyme disease is the most common tick-borne disease in the US and is also a significant veterinary problem due to a high infection rate of dogs and other domestic animals in endemic regions. The European market is equal to or greater th...
Published: Nov 3, 2011   |   Inventor(s):  
Category(s): Diagnostics, Research Materials
A Method for Generating Poroelastograms in Vivo
A METHOD FOR GENERATING POROELASTOGRAMS IN VIVO Background: Ultrasound elastograms in are generated by cross-correlating the sequentially-acquired post compression ultrasound data with the reference pre-compression ultrasound data, thus generating an image that allows for differentiation of tissues types, i.e. benign vs. malignant tumors. A ...
Published: Oct 24, 2011   |   Inventor(s):  
Category(s): Medical Devices, Software, Diagnostics
Enhancing MRI Contrast by Geometric Confinement of Small Imaging Agents within Nanoporous Particles
MRI Contrast Agents in NanoPorous Particles Market:­ Physicians use magnetic resonance imaging (MRI) to examine the state of a patient’s internal organs. Typically, MRI is performed to evaluate the state of a patient’s brain and spinal cord, heart and blood vessels, bones and joints, and other internal organs. The current market for MR...
Published: Oct 19, 2011   |   Inventor(s):  
Category(s): Diagnostics
Method to perform Axial-shear strain imaging for tumor classification
AXIAL SHEAR STRAIN ELASTOGRAPHY (ASSE) Background: Ultrasound elastography, now a well-established diagnostic technique, is expanding into everyday ultrasound machines used in all types of clinical practice. The basic elastography technique involves two images of a tissue in question – the first in a normal “before” state and the second aft...
Published: Oct 18, 2011   |   Inventor(s):  
Category(s): Diagnostics, Medical Devices, Software
Hyperplastic Vasculomyopathy Diagnostic
Market: In 2007 in the United States alone, it is estimated that direct and indirect costs of cardiovascular diseases is $481.8 billion. Each year hundreds of thousands of patients are diagnosed with vascular diseases such as myocardial infarction and stroke. Competitors and Current Problems: A subset of individuals may have a genetic predispo...
Published: Aug 22, 2011   |   Inventor(s):  
Category(s): Diagnostics
Elastography: Highly Sensitive Ultrasound Imaging of Tissue Elasticity In Vivo for Detection and Evaluation of Breast Cancer and Other Elastic Abnormalities
Market: Market reports indicate that the ultrasound market in Europe was estimated at $719.0 million in 2006, with growth expected to reach $1 billion in 2013. Similarly, the ultrasound market in the United States was estimated at $1.27 billion in 2003. With an estimated 31.2 million patient exams in 2004 conducted by traditional clinical ultra...
Published: Aug 8, 2011   |   Inventor(s):  
Category(s): Diagnostics, Medical Devices, Software
Methods and Compositions for the Detection of Functional Clostridium Difficile Toxins
Market and Background: Clostridium difficile (C. difficile) is the leading identifiable cause of nosocomial diarrhea worldwide due to its virulence, multi-drug resistance, spore-forming ability, and environmental persistence. This bacterium has been implicated as the causative organism for 10-25% of the reported cases of antibiotic-associated ...
Published: Jun 30, 2011   |   Inventor(s):  
Category(s): Diagnostics
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