Search Results - Therapeutics

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HER3 specific monoclonal antibodies for diagnosis and therapeutic use
Background HER-3 is a receptor in the tyrosine kinase family that is a key oncogenic protein in breast cancer as well as other cancers. HER-3 is centrally involved in signaling leading to tumor growth and has been implicated in resistance to cancer treatments, making it an attractive target for cancer therapies. Several drugs, including some in c...
Published: Nov 10, 2014   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics, Diagnostics
Phospholipid Associated 5-ASA for the Treatment of Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) which represents a spectrum of diseases of the lower GI tract, notably Ulcerative Colitis (UC) and Crohn’s Disease (CD), is one of the most common gastrointestinal (GI) afflictions in the United States and Europe. It is also noteworthy that the incidence of UC has increased 2-3 fold in China and other counties ...
Published: Sep 15, 2014   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
Human Neural Stem Cells Produced by Direct Programming from Somatic Cells
Scientific breakthroughs have allowed human neural stem cells to be created from a patient’s own somatic cells. Although these artificially created neural cells hold great promise for the treatment of spinal cord injury and neurological disorders, they are created by genetic manipulation of cells using viral vectors. These genetic manipulati...
Published: Apr 10, 2014   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
Antibiotic Microspheres For Treatment Of Infections And Osteomyelitis
More than 750,000 people in the United States have knees, hips, or shoulders replaced surgically each year. For about 30,000 of these patients the surgery results in osteomyelitis, a dangerous infection of the bone tissue. This infection results in repeat surgeries for repair, replacement, and sometimes even removal of the implant. To treat osteom...
Published: Mar 20, 2014   |   Inventor(s):  
Keywords(s):  
Category(s): Medical Devices, Therapeutics
Multistage Nanoparticle Drug Delivery Systems
The Market: The American Cancer Society estimates that in the United States alone, over 1,000,000 people are diagnosed with cancer. Many cancer deaths, specifically from cancers of the colon, breast, rectum, and uterine cervix cancers, could be significantly reduced with earlier detection and improved targeted delivery of chemotherapeutics. ...
Published: Mar 14, 2014   |   Inventor(s):  
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Category(s): Therapeutics, Drug Delivery
Diagnostic and Method for Detection of Ankylosing Spondylitis
diagnostic and method for detection of aNKYLOSING SPONDYLITIS Background: Ankylosing spondylitis (AS) is one of the most common causes of inflammatory arthritis. AS is characterized by spinal and sacroiliac joint inflammation which causes pain and stiffness and eventually leads to bony ankylosis. Hip and peripheral joints ar...
Published: Jun 3, 2013   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
Novel Compounds and Methods of Use for the Treatment and Prevention of Cancer via Inhibition of the K-Ras Pathway
Novel compounds and methods of use for the treatment and prevention of cancer via inhibition of the k-ras pathway Background: The Ras protein family members belong to a class of proteins called small GTPases and when activated by incoming signals, it subsequently switches on other genes involved in cell growth, differentiatio...
Published: Apr 2, 2013   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
Methods and composition for novel anti-cancer treatments
Background: The Wnt signaling pathway plays essential roles in development and is frequently hyperactivated in cancer cells as a driving mechanism. Nearly 90% of colon cancers, for examples are mutated in this pathway. However, direct targeting of this pathway for cancer drug discovery has been challenging due to receptor redundancy and compl...
Published: Mar 25, 2013   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics, Diagnostics
Compositions and Methods for Regulation of Stem Cell Survival, Proliferation, and Differentiation
Background: Regenerative medicine is the process of using stem cells or related products to repair or repopulate organs or tissues damaged by a disease. Stem cell-based regenerative therapies may be used to heal or treat a wide range of conditions including cardiovascular disease, cancer, osteoporosis, Alzheimer’s disease, Parkinson’s disease...
Published: Jan 9, 2013   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
Preparation and Use of Alveoar Cells to Treat Lung Disorders
Background Alveolar type II (ATII) cells have numerous functions related to lung homeostatsis; these include (i) acting as progenitors for alveolar type I (ATI) cells, which is particularly important during re-epithelialization of the lung after injury; (ii) synthesis and secretion surfactant proteins, which reduces surface tension and helps p...
Published: Jul 23, 2012   |   Inventor(s):  
Keywords(s): Therapeutics
Category(s): Therapeutics
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