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Novel Oncolytic Herpes Simplex Virus (oHSV) for Cancer Treatment
Researchers from UTHealth have developed a novel oncolytic viral therapy, oHSV-shPKR, which can inhibit tumor cells’ antiviral PKR activity, and increase oncolytic virus infection and replication in both oncolytic viral-resistant and sensitive cancer cells. This novel oHSV-shPKR therapy can significantly increase the anti-tumor immune response...
Published: 8/15/2023
|
Inventor(s):
Balveen Kaur
,
BangXing Hong
Keywords(s):
Category(s):
Biologics
,
Oncology
,
Therapeutics
Co-Administration of Oncolytic Herpes Simplex Virus (oHSV) with Cisplatin for Anti-Cancer Immunotherapy
Researchers from UTHealth and Ohio State University College of Medicine have collaborated to investigate the impact of oHSV therapy in combination with platinum agents using platinum-resistant high-grade serous ovarian carcinoma (HGSOC) as well as platinum-resistant ovarian clear cell carcinoma models. More importantly, they have developed a novel...
Published: 8/15/2023
|
Inventor(s):
Balveen Kaur
Keywords(s):
Category(s):
Therapeutics
,
Oncology
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