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Monoclonal antibodies against human and mouse leptin for therapeutic and diagnostic use.

BackgroundLeptin is a hormone produced by adipocytes and is elevated in obesity. The congenital lack of leptin results in obesity and the metabolism field widely accepts the concept. Upon cloning of the leptin gene, the original hope was that leptin would act as a break for further food intake and a trigger to increase energy expenditure. The hope was...

Published: 2/8/2024 | Inventor(s): Zhiqiang An, Philipp Scherer, Ningyan Zhang

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Category(s): Biologics, Oncology, Therapeutics, Metabolism